The ISL54220 is a single supply dual 2:1 multiplexer that can operate from a single 2.7V to 5.5V supply. It contains two Single Pole/Double Throw (SPDT) switches configured as a DPDT. The part was designed for switching or routing of USB High-Speed signals and/or USB Full-Speed signals in portable battery-powered products. The 6Ω switches can swing rail-to-rail and were specifically designed to pass USB Full-Speed data signals that range from 0V to 3.3V and USB High-Speed data signals that range from 0V to 400mV. They have high bandwidth and low capacitance to pass USB High-Speed data signals with minimal distortion. The digital logic inputs are 1.8V logic compatible when operated with a 2.7V to 3.6V supply. The ISL54220 has an output enable pin to open all the switches. The ISL54220 is available in 10 Ld 1.8mm x 1.4mm µTQFN, 10 Ld TDFN and 10 Ld MSOP packages. It operates over a temperature range of -40 °C to +85 °C.


  • High-speed (480Mbps) and full-speed (12Mbps) signaling capability per USB 2.0
  • 1.8V logic compatible (2.7V to +3.6V supply)
  • Enable pin to open all switches
  • Power OFF protection
  • D-/D+ pins overvoltage tolerant to 5.5V
  • -3dB frequency: 742MHz
  • Low ON capacitance at 240MHz: 4.2pF
  • Low ON-resistance at VDD = 5.5V: 4.5Ω
  • Low ON-resistance at VDD = 3.3V: 6.0Ω
  • Single supply operation (VDD): 2.7V to 5.5V
  • Available in µTQFN, TDFN and MSOP packages
  • Pb-free (RoHS compliant)
  • Compliant with USB 2.0 short circuit and overvoltage requirements without additional external components



  • MP3 and other personal media players
  • Cellular/Mobile phones
  • PDAs
  • Digital cameras and camcorders
  • USB switching


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